Searchable abstracts of presentations at key conferences in endocrinology

ea0049oc10.3 | Bone & Calcium Homeostasis | ECE2017

High prevalence of radiological vertebral fractures in patients with differentiated thyroid carcinoma undergoing L-thyroxine TSH-suppressive therapy

Formenti Anna Maria , Mazziotti Gherardo , Frara Stefano , Maffezzoni Filippo , Doga Mauro , Bertagna Francesco , Maroldi Roberto , Memo Maurizio , Giubbini Raffaele , Giustina Andrea

Thyroid hormones play a central role in the regulation of bone turnover and thyrotoxicosis is an established cause of secondary osteoporosis. Increased prevalence of reduced bone mineral density (BMD) has been reported even in patients with subclinical thyrotoxicosis such as those with differentiated thyroid carcinoma undergoing long-term L-thyroxine (L-T4) TSH-suppressive therapy. Morphometric vertebral fractures (VFs) are an early and clinically...